A Step Closer to Personalized Cancer Cure

An article published in the September 6 issue of Science Express discusses the breakthrough achieved by the Johns Hopkins Kimmel Cancer Center scientists who have completed the first draft of the genetic code for breast and colon cancers.

[The study] identifies close to 200 mutated genes, now linked to these cancers, most of which were not previously recognized as associated with tumor initiation, growth, spread or control.

Because no two patients are the same with breast and colon cancer, therapies are very hard to administer. Ultimately, once we know enough about all of the implicated genes, it will be possible to find out which of a particular patient’s genes are affected and treat only those genes. From the BBC Article:

Dr Anna Barker of the National Cancer Institute said: “Maximising the numbers of targets available for drug development in a specific cancer means that patients will ultimately receive more personalized, less toxic therapies.”

She also said: “In the future, scientists hope to be able to tailor plans for preventing or treating cancer to each person’s individual genetic profile. Studies like this can help us to accomplish this goal.”

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Saturday Night Puzzle: Birthday Sharing Party

And we have an right answer! Thanks to both Eddie and John for their right answer. Very well done!

You are at a party with a friend and 30 people are present including you and the friend. Your friend wants to make a wager with you if there are two people that share their birthday date, he will give you 100$, however, you shall give him 100$ if nobody shares their birth date. Would you accept the wager ? Explain why.

Thursday Morning Puzzle: The Counterfeit Bill

I’ve had a couple of suggestions for the solution of this puzzle. Thanks to Heather, Eddie, and John for trying to solve the puzzle! I’ve just posted the solution in the comments. You can access the comment page of this article by clicking on the ‘comment’ label under the title.

A shop manager bought a box of chocolate for 2$ each; he sold the chocolate for 2.50$ each. One day, a person comes into the shop and buys this kind of chocolate with a 50$ note; the manager didn’t have enough change and so the manager went to the shop next door and swapped the note with some changes. He gave that costumer the chocolate with 47.50$ of change and the costumer left. Few minutes later, the shop assistant next door found the manager and told him that note is a forgery, he asked the manager to return 50$ and so the manager did. How much has the manager lost altogether?

I will post the answer to this Puzzle in exactly 4 days (Sunday, October 29). I hope to get some guesses for the correct answer by then. Stay tuned because I will be publishing a couple of my favourite puzzles in the next couple of days.

My Second Interview with Accenture

I didn’t want to say much about this second interview here. However, seeing as my first post on the subject seems to have helped a couple of people out there, I thought I should share a little something for the second round interviews also.

My second interview was with a different person from Accenture, Montreal. He was really nice, but we skipped the chatting from the first interview and dove right into the subject matter: Behaviour, Behaviour, Behaviour. So I will only give you one piece of advice for this second interview: Prepare at least 5 projects from which you remember a large amount of details (because, yes, they will dig really deep!), and be ready to answer a couple of questions using those projects. I also suggest visiting quintcareers.com’s sample behavioural questions to get an idea of the kind of questions you will be asked. You should be able to find all of the information you need in order to do well in behavioral interviews on that website. You should also visit the section on Second Interview Do’s and Don’ts from the same website.

Just to give you an idea of the kind of questions they may ask you. I was asked to “talk about a time you had to talk about the difficulties you were facing in a project”. They asked me a lot of questions about the said project, what was it, why was it difficult, but they also asked me to explain in detail how I was feeling when I was talking to my employer. Needless to say, it was very difficult to remember.

Oh and one last thing. Don’t ever lie about a project. It’s way better to be honest. I told them at one point that I didn’t remember this project in that much detail. They said “no problem, we’ll change question”. After all, they are not there to torture you, they are only there to find out more about you. If you lie, then all they’ll find out about you is that you are a liar… and that would definitively rule out a third round interview! Having said that, I would recommend studying your past five projects you’ve done and try to remember as much details as possible.

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Phone Interview with Nuance

The phone interview is officially scheduled for Tuesday October 24th at 20h00. I can’t wait because I have many questions in mind already.

Nuance Communications, Inc Things are advancing fast on my job search so far in October. Since I learned from my friend Jean-Philipe, through our common friend Sylvain, that Nuance Communications is looking for a person with a Mathematical and Programming background to fill in a position as a Speech Scientist, I have been super excited about this opportunity. First, I did some research on the subject and talked with Jean-Philipe about the position. I also read a little bit about the company and the science behind Speech Recognition. I had no idea it was such an interesting field of Mathematical applications. Anyways. Then I sent my Resume and nice little cover letter (which was appreciated by the recruiter apparently!).

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